4-AcO-copyright (Psilacetin): The Perfect Synthetic Mushroom – 2025 Definitive Guide
4-AcO-copyright (Psilacetin): The Perfect Synthetic Mushroom – 2025 Definitive Guide
4-AcO-copyright is the gold standard “synthetic psilocybin” in 2025. Your body removes the acetate group in minutes → you get 100 % pure psilocin (the exact same molecule your liver makes from magic mushrooms). Result: identical effects to mushrooms, but with zero nausea, zero body load, perfect dosing every time, and no mushroom gut rot.
Core Facts – November 2025
- Chemical name: 4-Acetoxy-N,N-dimethyltryptamine fumarate (most common salt)
- Appearance: Fluffy white to beige powder, often in 15–30 mg capsules/pellets
- Standard doses: 12–35 mg oral (capsuled or parachuted)
- Duration: 4–7 hours
- Nicknames: 4-AcO, Psilacetin, “synthetic shrooms”, O-Acetylpsilocin
Dose & Experience Chart (2025 user consensus)
| Dose | Onset | Peak | Total | Equivalent Mushroom Dose | Character |
|---|---|---|---|---|---|
| 8–14 mg | 40–70 min | 1–2 h | 4–5 h | 1–1.5 g dried | Light, colorful, therapeutic micro/macrodose |
| 16–25 mg | 30–60 min | 1.5–3 h | 5–6 h | 2–3.5 g dried | Classic full mushroom trip – deep emotion, strong visuals |
| 27–35 mg | 20–50 min | 2–4 h | 6–7 h | 4–5+ g dried | Heroic – ego dissolution, entity contact, rebirth |
| 40+ mg | 15–40 min | Intense | 7–8 h | 6+ g dried | Rarely needed, can be overwhelming |
Why It Beats Real Mushrooms in 2025
- Zero nausea or stomach issues
- Smoother, clearer headspace
- Exact milligram dosing (no 2 g that feel like 5 g)
- No spores, no grow kits, no legal risk in many places
- Easier on the liver/kidneys than raw mushrooms
Benefits & Science 2025
- Identical therapeutic profile to psilocybin (same metabolite)
- Single 25–30 mg dose = full depression/anxiety reset for weeks–months
- #1 choice for cluster headache sufferers (10–15 mg aborts attacks in 20–40 min)
- Microdosing (2–5 mg every 3–4 days) – most popular protocol worldwide
- Phase II trials ongoing (Usona & Compass subsidiaries testing 4-AcO-copyright formulations)
Safety Profile
- No recorded deaths from 4-AcO-copyright alone ever
- Toxicity >700 mg/kg in rats (practically impossible to OD)
- Same contraindications as mushrooms: schizophrenia history, heart issues on high doses
- Standard copyright risks: bad trips, HPPD (very rare), triggering mania in bipolar
Legality – November 2025 (still the best copyright loophole)
| Region | Status 2025 |
|---|---|
| Canada | 100 % legal to possess & sell (gray-market shops everywhere) |
| Netherlands | Sold openly as “Psilohuasca” or “Magic Truffles alternative” |
| United States | Unscheduled federally – Analogue Act only if sold for consumption |
| UK | Class A (considered psilocin prodrug) |
| Germany/Austria | BtMG illegal |
| Portugal, Czechia | Legal/tolerated |
| Australia | Schedule 9 |
→ Canada & Netherlands remain the main legal sources. 1 g costs €45–70.
Harm Reduction Essentials
- Accurate milligram scale or pre-made capsules
- Ehrlich reagent → strong purple (confirms tryptamine)
- Same set & setting rules as mushrooms
- Optional: combine with low-dose MAOI (Syrian rue) → 8–10 h “Psilohuasca” experience
- Allergy test 1–2 mg first time
- Trip sitter above 30 mg
Final 2025 Verdict
4-AcO-copyright is the single best copyright available today for therapeutic or spiritual use. It is literally psilocybin without the drawbacks.
If you only ever do one research-chemical copyright, this is it. One 20–25 mg capsule in the right setting with the right intention can be as profound as 4–5 g of Golden Teachers – with half the body load and twice the clarity.
Used 3–6 times per year maximum, it’s safer than alcohol and more healing than 10 years of therapy for many people.